No-Reflow

Cardioprotection via brain-gut-heart signalling: GLP-1 activates KATP channels in coronary pericytes

Coronary no-reflow, which impacts roughly half of patients following artery reopening for myocardial infarction, remains a major clinical challenge. Here we demonstrate that the incretin GLP-1 (glucagon-like peptide 1) can be used to protect the …